While most probiotic supplements contain strains of bacteria that both reduce histamine and produce histamine to allow for a diverse probiotic supplement, it does not help the individual who has symptoms of histamine intolerance and is looking for the best probiotic supplement for histamine intolerance.
The best probiotic strains for histamine intolerance are Bifidobacterium infantis, Bifidobacterium longum, lactobacillus brevis and lactobacillus plantarum which are found in Probiota HistaminX.
Some common probiotics that can produce histamine in the gut include lactobacillus casei and lactobacillus bulgaricus. None of these strains of probiotics are found in Probiota HistaminX. While these strains of probiotics still have beneficial properties they may not be best for the histamine sensitive individual.
Some other bacteria that have been shown to produce histamine in large amounts include oxytoca, citrobacter freundii and enterobacter cloacae. These bacteria are often found in higher levels in people with gut dysbiosis and SIBO.
Utilizing a probiotic with bacteria that helps to reduce histamine in the gut helps to balance the microflora in the gut and ensures that DAO enzyme and HNMT enzyme are not overloaded with histamine to metabolize from the gut. Probiota is one of the best probiotics for SIBO and histamine intolerance and I have seen great results with several clients and customers using this probiotic. I am often wary of using probiotics especially when I suspect SIBO may be present but this probiotic is very well tolerated and the strains have been shown to reduce histamine in the body.
Histamine block contains the enzyme diamine oxidase which helps to metabolize food sources of histamine and histamine coming from the gut and outside the cell.
The DAO enzyme is found in large amounts in the intestinal lining but if the gut lining is damaged due to a leaky gut or even excess histamine caused from bacteria or mast cell activation a loss of the DAO enzyme can occur and thus the body has a decreased ability to metabolize and reduce histamine in the body and thus contributing to histamine symptoms.
Some individuals may have SNP’s in the DAO enzyme therefore genetically have a decreased ability to metabolize external histamine from foods and bacteria in the gut and thus easily get overwhelmed in general or when eating high histamine foods.
Supplementing with diamine oxidase helps to metabolize external histamine from food sources and in the gut.
Vitamin c and histamine intolerance
Mast cells are immune cells that when stimulated release pro-inflammatory compounds such as histamine as one of the inflammatory compounds released. When mast cells are activated reactive oxygen species are produced and vitamin C is an antioxidant that protects the immune cells from reactive oxygen species.
Vitamin c has been shown to decrease bronchial hypersensitivity and helps to reduce the duration of the common cold, sneezing, coughing, runny nose and other symptoms related to mast cell activation and the release of histamine.
Seeking health’s liposomal vitamin c plus is an amazing vitamin c for histamine intolerance for several reasons. First being a liposomal vitamin c makes this vitamin c readily absorbed and utilized by the body as the phosphatidylcholine acts as a delivery mechanism to get vitamins inside the cell.
This vitamin c also contains lutein and quercetin which both help with stabilizing mast cells that produces histamine to help with allergy like symptoms of histamine intolerance and is mixed with bioflavonoids which are also needed for optimal utilization of vitamin c in the body
The phosphatidylcholine found in this liposomal vitamin c also indirectly supports the HNMT enzyme which is responsible for breaking down histamine found inside the cell as opposed to outside the cell. The HNMT enzyme requires a methyl donor called SAMe as a cofactor for this gene to function. 70-80 percent of SAMe is used to make phosphatidylcholine so by providing the body with phosphatidylcholine in this liposomal vitamin c the body does not need to make as much phosphatidylcholine therefore SAMe is freed up to work elsewhere in the body such as for the HNMT enzyme to work and reduce histamine in the body.
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