I learned about the world of genetics through Dr. Ben Lynch and his book Dirty Genes. After reading Dirty Genes, I was blown away by the connection between common health problems and unique genetic SNPs.
I decided to take Dr. Ben Lynch’s courses to deepen my understanding of the connection between genetics, nutrition, and health problems such as SIBO, histamine intolerance, and inflammation.
The primary benefit of genetic testing is to see where your unique susceptibilities lie. You can then support your genetic SNPs through diet, lifestyle, and nutritional supplements.
The body is interconnected in so many ways. Using my nutritional knowledge combined with Ben Lynch’s genetic courses helped me to see the various ways in which the body is connected and why nutrition is so important.
We need nutrients so our genes can function. Bottom line: eat real food with nutrients to support your body’s ability to function. A loss of function can occur in the presence of a nutritional deficiency. Loss of function on the cellular and genetic level shows up as symptoms in the body.
For example, the famous MTHFR gene is responsible for converting folate from leafy greens into methylfolate. The nutritional cofactor for the MTHFR gene to function is vitamin b2.
Thus the best diet for someone with an MTHFR gene mutation is a diet high in vitamin B2 and folate. Symptoms associated with MTHFR gene mutation worsen if vitamin B2 or folate is deficient.
The MTHFR gene is one gene among many clinically relevant SNPs involved in the production of SAMe, which supports over another 200 plus functions.
The magic happens when you start to fit all the pieces of the genetic SNP puzzle together. When you see the big picture and how your diet and lifestyle affect your genes, you can then make better choices to optimize your health.
The power lies in understanding the connection between genes and the body as a whole harmonious system working together. Genetic testing for SNPs can help you to personalize your unique dietary needs to support genetic SNPs with the nutritional cofactor for the gene to function.
Genetic SNPs in the PEMT Gene
The gene that I am obsessed with is the PEMT gene. PEMT gene mutation symptoms include fatty liver, SIBO, and a sluggish gallbladder. Optimal PEMT gene function is crucial for good gut health and weight loss. The nutrient choline is important for the PEMT gene.
SAMe is the cofactor for the PEMT. MTHFR is a gene in the methylation pathway that helps to support the production of SAMe. SAMe is the co-factor for the PEMT gene. The connections all start to click together.
SNPs in the MTHFR gene, methylation pathway, or PEMT gene can increase the likely hood of someone developing SIBO. Small intestinal bacterial overgrowth is not fun and has many uncomfortable symptoms.
PEMT gene mutation can cause a sluggish gallbladder and SIBO. The underlying causes of SIBO no one is talking about is poor methylation, PEMT gene mutations, and a sluggish gallbladder. This article explains the connection between MTHFR and SIBO. Read it!
DAO SNPs and Histamine Intolerance
A DAO SNP is often associated with symptoms of histamine intolerance. The DAO enzyme helps to metabolize histamine from food and the gut.
High histamine foods can become extremely problematic for someone with a DAO gene SNP. High histamine foods such as fermented foods, cured meats, aged cheese, wine, bone broth, and soy sauce can cause histamine symptoms.
Common Symptoms of Histamine Intolerance Include:
- Itchy skin
- Water Eyes
- Abdominal Pain
Using a diamine oxidase enzyme supplement with food can help reduce symptoms of histamine intolerance. Reducing high histamine foods is beneficial for histamine intolerance symptoms. Pretty cool how personalized dietary tips and targeted supplements can reduce histamine symptoms.
SOD SNPs and Inflammation
SNPs in the SOD gene are associated with increased levels of reactive oxygen species. These are the nasty free radicals that damage tissues. Inflammation from elevated ROS inhibit many genes and are the root cause of many health conditions.
Inflammatory health conditions such as arthritis are associated with elevated reactive oxygen species. Manganese is the cofactor for the Mn-SOD gene. This mineral is abundant in blackberries. If you have inflammation in your body it is very beneficial to eat antioxidant fruits.
Taking a superoxide dismutase supplement helps break down reactive oxygen species. It is the increase in reactive oxygen species that cause inflammation.
For more information on genetic testing for SNPs such as SOD, DAO, MTHFR, PEMT, and more, check out this post: What to expect from your strategene report. Genetic testing is a powerful tool to help you optimize and personalize your health.